WebMD Medical News
Laura J. Martin, MD
Dec. 6, 2010 -- Women who had restless legs syndrome (RLS) while pregnant were four times more likely to have the condition again after their pregnancies, and were three times more likely to have the chronic form of the condition, according to a small European study.
Researchers led by Mauro Manconi, MD, PhD, from Vita-Salute University in Milan, Italy, and colleagues compared 74 women who had experienced restless legs syndrome during their pregnancies and 133 women who had not.
Restless legs syndrome is a neurological disorder characterized by uncomfortable sensations in the legs that sometimes lead to a feeling of needing to move the legs for relief. Symptoms are often worse during the night. The disorder affects about 10% of the U.S. population.
Symptoms of restless legs syndrome can arise during pregnancy and then disappear after childbirth. The incidence of restless legs syndrome among pregnant women ranges from 26% to 30% and often peaks during the third trimester, according to the researchers.
Study participants were surveyed and asked about their medical history, including symptoms of restless legs syndrome and medications they used within two days after delivery. The women were then followed for an average of 6.5 years to see who developed recurrent restless legs syndrome.
The researchers found that:
The study results suggest pregnancy-related restless legs syndrome may signal a risk for developing future transient episodes or even the chronic form of the disorder.
The findings are published in the Dec. 7 issue of Neurology.
“This is the first long-term study to look at a possible connection between restless legs syndrome in pregnancy and repeat occurrences in later years or future pregnancies,” writes study researcher Mauro Manconi, MD, PhD, with Vita-Salute University in Milan, Italy. “Most of the time, when a woman experiences RLS in pregnancy, it disappears after the baby is born. However, our results show that having the condition during pregnancy is a significant risk factor for a future chronic form or the short-term form in other pregnancies down the road. Women who experience RLS should still be reassured that symptoms will probably disappear after delivery but may reappear later on.”
SOURCES:Manconi, M. Neurology, Dec. 7, 2010; pp 2117-2120.National Institute of Neurological Disorders and Stroke.
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